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DeCS
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Descriptor Inglés:
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Alpha-Ketoglutarate-Dependent Dioxygenase FTO
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Descriptor Español:
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Dioxigenasa FTO Dependiente de Alfa-Cetoglutarato
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Descriptor Portugués:
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Dioxigenase FTO Dependente de alfa-Cetoglutarato
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Sinónimos Inglés:
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AlkB Homolog 9 Protein
Alpha-Ketoglutarate-Dependent Dioxygenase
Fat Mass and Obesity Associated (FTO) Protein
Fat Mass and Obesity Associated Protein
Alpha Ketoglutarate Dependent Dioxygenase
Alpha Ketoglutarate Dependent Dioxygenase FTO
Dioxygenase, Alpha-Ketoglutarate-Dependent
FTO, Alpha-Ketoglutarate-Dependent Dioxygenase
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Categoría:
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D08.811.074.062.968
D08.811.682.662.582.242
D08.811.682.690.416.139.992
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Definición Inglés:
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A dioxygenase that repairs alkylated DNA and RNA by oxidative demethylation. It has highest activity towards single-stranded RNA containing 3-methyluracil, followed by SINGLE-STRANDED DNA containing 3-methylthymine and specifically demethylates N(6)-methyladenosine (m6A) RNA, the most common internal modification of MESSENGER RNA (mRNA) in higher EUKARYOTES. It contributes to the regulation of the global metabolic rate, energy HOMEOSTASIS, as well as body fat accumulation by regulating the differentiation of ADIPOCYTES into BROWN FAT CELLS or WHITE FAT CELLS. |
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Nota Histórica Inglés:
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2017
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Calificadores Permitidos Inglés:
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Número del Registro:
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56463
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Identificador Único:
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D000071516
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Ocurrencia en la BVS:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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